CHROMOSOMAL ALTERATION AND THE DEVELOPMENT OF TUMORS XIV. COMPARATIVE IDIOGRAM ANALYSIS OF SEVERAL SUBLINES OF MOUSE LYMPHOCYTIC NEOPLASM, P388, GROWING IN VIVO AND IN VITRO

Publisher Website
Google Scholar
Abstract
Karyotypes in several lines of the mouse lymphocytic neoplasm, P388, growing in vivo and in vitro, were examined. The chromosome alteration was observed frequently in natural populations of tumor cells growing suggesting that tumors are usually in heterogenous condition, and that the most vigorous cell type may control the mode of a cell population under certain conditions.