Adrenal Function in Pantothenic Acid Deficiency
- 31 January 1953
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 172 (2) , 259-264
- https://doi.org/10.1152/ajplegacy.1953.172.2.259
Abstract
Rats put on a pantothenic acid-deficient diet and examined at intervals over a 90-day period showed a progressive decline in adrenal cholesterol concn., no alteration in adrenal ascorbic acid concn., an increase in enzyme activity (succinic dehydrogenase) of the adrenal up to the 50th day with a decline thereafter, and no loss in the ability to react to stress as judged by the discharge of ascorbic acid. However, these changes were only associated with a deficiency of pantothenic acid and not with a deficiency of other B complex factors.Keywords
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