Identification of a Rhodococcus Gene Cluster Encoding a Homolog of the 17-kDa Antigen of Brucella and a Putative Regulatory Protein of the AsnC-Lrp Family
- 1 July 1996
- journal article
- research article
- Published by Springer Nature in Current Microbiology
- Vol. 33 (1) , 26-30
- https://doi.org/10.1007/s002849900068
Abstract
By sequence analysis, a gene encoding a homolog of the 17-kDa protein antigen of the Gram-negative pathogen Brucella abortus (Hemmen et al., Clin Diagn Lab Immunol 2: 263, 1995) was identified in the nocardioform actinomycete Rhodococcus sp. NI86/21. Database searching also revealed a partial human cDNA sequence for a putative eukaryotic homolog of this presumptive Brucella-specific protein. These proteins display a low but significant level of similarity with lumazine synthases involved in bacterial riboflavin biosynthesis. In the upstream region, a Rhodococcus gene for a putative regulatory protein of the AsnC family is located.This publication has 7 references indexed in Scilit:
- The first characterization of a eubacterial proteasome: the 20S complex of RhodococcusCurrent Biology, 1995
- Degradation of the thiocarbamate herbicide EPTC (S-ethyl dipropylcarbamothioate) and biosafening by Rhodococcus sp. strain NI86/21 involve an inducible cytochrome P-450 system and aldehyde dehydrogenaseJournal of Bacteriology, 1995
- Basic local alignment search toolJournal of Molecular Biology, 1990
- Nucleotide sequence of the putative regulatory gene and major promoter region of the Streptomyces griseus glycerol operonGene, 1990
- Improved detection of helix-turn-helix DNA-binding motifs in protein sequencesNucleic Acids Research, 1990
- Structure and regulation of controlling sequences for the Streptomyces coelicolor glycerol operonJournal of Molecular Biology, 1988
- AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coliJournal of Bacteriology, 1985