Reflections on the Pathologic Physiology of Atherosclerosis

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Abstract
The Serum LipidsOf the three major classes of nutrients, amino acids (protein), glucose (carbohydrate) and fatty acids (fat), only the fatty acids present a problem in water solubility.28 To be able to absorb, transport and utilize fatty acids and other lipids, man has had to evolve rather elaborate (and vulnerable) mechanisms for making these water-immiscible or hydrophobic materials compatible with a system whose basic common medium is water. Indeed, for biochemical changes to occur, it is usually necessary for the reacting substances to be in solution in the same medium.The mechanisms used to deal with the water-insoluble fatty . . .