Distribution of Mutations in Human Thymidylate Synthase Yielding Resistance to 5-Fluorodeoxyuridine

This publication has 22 references indexed in Scilit:

• Crystal structure of a deletion mutant of human thymidylate synthase Δ (7–29) and its ternary complex with Tomudex and dUMP
  Protein Science, 2001
• Human Thymidylate Synthase Is in the Closed Conformation When Complexed with dUMP and Raltitrexed, an Antifolate Drug^,
  Biochemistry, 2001
• Mechanisms of Acquired Resistance to Thymidylate Synthase Inhibitors: The Role of Enzyme Stability
  Molecular Pharmacology, 1999
• Crystal Structures of Rat Thymidylate Synthase Inhibited by Tomudex, a Potent Anticancer Drug^,
  Biochemistry, 1998
• Probing the Folate-binding Site of Human Thymidylate Synthase by Site-directed Mutagenesis
  Journal of Biological Chemistry, 1998
• THYMINE METABOLISM AND THYMINELESS DEATH IN PROKARYOTES AND EUKARYOTES
  Annual Review of Microbiology, 1998
• Random Sequence Mutagenesis and Resistance to 5-Fluorouridine in Human Thymidylate Synthases
  Journal of Biological Chemistry, 1998
• Isolation and Characterization of Thymitaq (AG337) and 5-Fluoro-2-deoxyuridylate-resistant Mutants of Human Thymidylate Synthase from Ethyl Methanesulfonate-exposed Human Sarcoma HT1080 Cells
  Published by Elsevier ,1998
• Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site
  Biochemistry, 1995
• THE CATALYTIC MECHANISM AND STRUCTURE OF THYMIDYLATE SYNTHASE
  Annual Review of Biochemistry, 1995