Ectopic Production of Parathyroid Hormone by Carcinoma of the Breast

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Abstract
HYPERCALCEMIA is a common complication of breast cancer usually associated with radiologic evidence of skeletal metastases or the administration of hormone therapy.1 , 2 Although the neoplasms associated with ectopic production of parathyroid hormone (PTH) have recently been reviewed,3 there is a striking absence of breast cancer among them. Furthermore, carcinoma of the breast has not been included among the tumors in which the presence of immunoreactive PTH-like activity has been documented.4 , 5 In the following ease the tumor tissue contained a PTH-like substance.Case ReportA 44-year-old premenopausal woman underwent a radical mastectomy in 1966 for removal of a duct-cell carcinoma of . . .