5′-Terminal structure and mRNA stability
- 1 March 1977
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 266 (5599) , 235-239
- https://doi.org/10.1038/266235a0
Abstract
Reovirus mRNA with 5''-terminal m7GpppGm or GpppG are more stable than mRNA containing unblocked ppG 5''-ends when injected into Xenopus laevis oocytes or incubated in cell-free protein synthesizing extracts of wheat germ and mouse L cells. The greater stability of mRNA with blocked 5'' termini is not dependent upon translation but seems to result from protection against 5''-exonucleolytic degradation.This publication has 24 references indexed in Scilit:
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