ANTIBACTERIAL ACTIVITY ASSOCIATED WITHLACTOBACILLUS ACIDOPHILUS
- 1 October 1959
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 78 (4) , 477-484
- https://doi.org/10.1128/jb.78.4.477-484.1959
Abstract
Strains of L. acidophilus obtained from mice, rats, rabbits, hamsters, and man were found to produce an antimicrobiol agent, termed lactocidin, when grown on liver-veal agar. Two methods of assay were devised and employed to pick the most productive strains, isolated from rabbit, and to follow purification. Lactocidin was concentrated 2500-fold. Crude lactocidin had a broad antibacterial spectrum and was active in serum. Purified lactocidin was unstable and inactive in serum.Keywords
This publication has 21 references indexed in Scilit:
- Beneficial Effect of Quinoxaline 1,4-di-N-Oxide in Radiation Injury in Mice.Experimental Biology and Medicine, 1957
- ColicinsAnnual Review of Microbiology, 1957
- A LACTOBACILLUS PREPARATION FOR USE WITH ANTIBIOTICSThe Lancet, 1957
- The effect of an antibiotic on the susceptibility of the mouse's intestinal tract to Salmonella infection.1956
- The Characteristics of Lactobacillus acidophilus and Lactobacillus bulgaricusJournal of General Microbiology, 1955
- Characteristics of Antibiotic-Producing Strains of the Ocular Bacterial FloraThe Journal of Immunology, 1953
- Possible Identity of ‘Lactobacillin’ with Hydrogen Peroxide produced by LactobacilliNature, 1952
- Microbiological synthesis of C14-uniformly labeled l(+)- and d(−)- lactateArchives of Biochemistry and Biophysics, 1952
- A Selective Medium for the Isolation and Enumeration of Oral LactobacilliJournal of Dental Research, 1951
- Antagonistic Relationship Between Oral OrganismsJournal of Dental Research, 1949