Reciprocal Changes in Sensitivity to MCH and Noradrenaline After Denervation of Teleost Melanophores

Abstract
Melanophores of isolated fish scales survive for weeks in a culture medium. During this isolation period a progressive increase in sensitivity to noradrenaline (NA) takes place. In the present study, a 100-fold increase in sensitivity to NA was found after 9 days. However, at the same time, a 12-fold decrease in sensitivity to MCH was detected.