The Stereochemistry of Sweetness
- 1 January 1975
- journal article
- Published by Wiley in Starch ‐ Stärke
- Vol. 27 (2) , 51-56
- https://doi.org/10.1002/star.19750270206
Abstract
Conformational analogies between sugars, deoxy sugars, substituted sugars, glycosides and cyclitols are examined in relation to current hydrogen bond theories of sweetness. Although the sensory properties of saporous molecules are probably multifunctional in origin, hydrophilic and lipophilic substituents vary in their effects. The former depend on configuration, whereas the latter may either enhance sweetness by strengthening binding to the taste bud protein, or cause re‐alignment of the molecule, eliciting a bitter response.Keywords
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