Metabolic products of microorganisms. 200. Isolation and characterization of niphithricins A, B, and elaiophylin, antibiotics produced by Streptomyces violaceoniger.
- 1 January 1981
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 34 (9) , 1107-1118
- https://doi.org/10.7164/antibiotics.34.1107
Abstract
Fermentations of S. violaceoniger TU 905 produce the antifungal antibiotics niphithricins A, B, elaiophylin and nigericin. The niphithricins were characterized as new macrolide antibiotics and the previously unknown structure of elaiophylin was determined to be a macrodiolide. The niphithricins were biologically active against gram-positive bacteria and fungi. The mode of action is attributed to an alteration of the membrane permeability.This publication has 13 references indexed in Scilit:
- Molluscicidal saponins from cornus florida L.Helvetica Chimica Acta, 1978
- Mode of action of iturin A, an antibiotic isolated from Bacillus subtilis, on Micrococcus luteusBiochemical and Biophysical Research Communications, 1978
- Polyene antibiotics. VII. Carbon-13 nuclear magnetic resonance evidence for cyclic hemiketals in the polyene antibiotics amphotericin B, nystatin A1, tetrin A, tetrin B, lucensomycin, and pimaricin.The Journal of Antibiotics, 1976
- Effect of cholesterol incorporation on the sensitivity of liposomes to the polyene antibiotic, filipinBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1968
- The Action of Polyene Antibiotics on Phospholipid-Cholesterol StructuresJournal of Biological Chemistry, 1967
- Production and Ultrastructure of Lysozyme and Ethylenediaminetetraacetate-Lysozyme Spheroplasts of Escherichia coliJournal of Bacteriology, 1967
- EFFECT OF POLYENE ANTIBIOTICS ON PROTOPLASTS OF NEUROSPORA CRASSAJournal of Bacteriology, 1962
- ALTERATIONS IN THE PERMEABILITY OF NEUROSPORA CRASSA DUE TO POLYENE ANTIBIOTICSJournal of Bacteriology, 1961
- A modified ninhydrin colorimetric analysis for amino acidsArchives of Biochemistry and Biophysics, 1957
- The Assimilation of Amino-acids by Bacteria: 2. The Action of Tyrocidin and some Detergent Substances in Releasing Amino-acids from the Internal Environment of Streptococcus faecalisJournal of General Microbiology, 1947