Abstract
It is clear that a syndrome of increased cerebrospinal fluid pressure without focal brain findings can be seen in occlusive disease of the venous outflow system from the brain. Six cases of metastatic malignancy elsewhere have been presented with increased cerebrospinal fluid pressure, normal ventricular system, and evidence of venous sinus disease. In patients with known neoplasms, the most likely cause of increased intracranial pressure is a mass lesion involving the cerebrum, cerebellum, or brainstem. If the pneumoencephalogram reveals a normal ventricular system, occlusive venous disease should be considered. Angiography is the only clinical method of definitely establishing the diagnosis. Further developments in angiography are necessary, but even our present techniques may show definite abnormalities in such patients.