Yersinia enterocoliticaInvasin-Dependent and Invasin-Independent Mechanisms of Systemic Dissemination

Abstract
We report here invasin-dependent and invasin-independent mechanisms in which the enteropathogenYersinia enterocoliticais able to disseminate from the lumen of the small intestine to the spleen. The invasin-dependent route is clearly discernible in mice devoid of intestinal Peyer's patches and mesenteric lymph nodes.