ROLE OF T-LYMPHOCYTES IN COLLAGEN-II INDUCED ARTHRITIS IN RATS
- 1 January 1983
- journal article
- research article
- Vol. 51 (1) , 117-125
Abstract
Functional T cells were needed for the development of arthritis since none of the 14 nude rats injected with collagen type II developed arthritis, while 11 of 14 of their normal counterparts did. With the help of antibodies specific for Ia antigens and different T cell subsets in the rats, an immunohistochemical method was used to demonstrate that T cells, predominantly of the helper type, and anti-Ia reactive non-T cells were abundant in the arthritic synovial tissue.This publication has 27 references indexed in Scilit:
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