Purealidin S and Purpuramine J, Bromotyrosine Alkaloids from the Fijian Marine Sponge Druinella sp.
- 22 October 2002
- journal article
- review article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 65 (12) , 1798-1801
- https://doi.org/10.1021/np020275n
Abstract
Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.Keywords
This publication has 22 references indexed in Scilit:
- Chemistry of Verongida Sponges. 9. Secondary Metabolite Composition of the Caribbean Sponge Aplysina cauliformisJournal of Natural Products, 1999
- A New Dibromotyrosine-Derived Metabolite from the Sponge Psammaplysilla purpureaJournal of Natural Products, 1998
- Three New Alkaloids from the Marine Tunicate Cystodytes violatinctusThe Journal of Organic Chemistry, 1998
- A New Bastadin from the Sponge Psammaplysilla purpureaJournal of Natural Products, 1993
- 11-Oxoaerothionin: A Cytotoxic Antitumor Bromotyrosine-Derived Alkaloid from the Caribbean Marine Sponge Aplysina lacunosaJournal of Natural Products, 1992
- Fistularin 3 and 11-Ketofistularin 3. Feline Leukemia Virus Active Bromotyrosine Metabolites from the Marine Sponge Aplysina archeriJournal of Natural Products, 1992
- Araplysillins-I and-II: Biologically active dibromotyrosine derivatives from the spongePsammaplysilla arabicaCellular and Molecular Life Sciences, 1990
- Two New Bromotyrosine-Derived Metabolites From an Australian Marine Sponge, Aplysina spAustralian Journal of Chemistry, 1989
- Proton and carbon-13 assignments from sensitivity-enhanced detection of heteronuclear multiple-bond connectivity by 2D multiple quantum NMRJournal of the American Chemical Society, 1986
- Considered stable carbocations. 262. anti-Tricyclo[5.1.0.03,5]octa-2,6-diyl dications. Novel bis(cyclopropylcarbinyl) dicationsJournal of the American Chemical Society, 1985