The Survival of Mammary Cells Following Irradiation in Vivo: A Directly Generated Single-Dose-Survival Curve

Abstract
A single-dose-radiation-cell-survival curve was generated for rat mammary gland cells. The methodology employed relied on the quantitative transplantation of enzymatically prepared monodispersed cells from irradiated rats into recipient rat fat pads. A positive endpoint consists of the formation of morphologically and functionally normal mammary tissue. The survival curve generated under the specific hormonal conditions described had a Do of 129 rad and an extrapolation value of 6.