Induction of Ovulation in Immature Hypophysectomized Rats
- 5 February 1960
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 131 (3397) , 357-359
- https://doi.org/10.1126/science.131.3397.357
Abstract
Immature rats given minute doses of highly purified pituitary gonadotropins (follicle-stimulating hormone and luteinizing hormone) 7 to 100 days after hypophysectomy ovulated and formed corpora lutea. Neither hormone alone was effective. Luteinizing hormone repaired in part the atrophied theca interna and interstitial tissue, and follicle-stimulating hormone stimulated the development of the granulosa cells.Keywords
This publication has 3 references indexed in Scilit:
- Effect of Interval Between Hypophysectomy and Injection of Gonadotrophin on Ovulation in the Rat.Experimental Biology and Medicine, 1947
- GONADOTROPINS OF THE SWINE PITUITARY I. VARIOUS BIOLOGICAL EFFECTS OF PURIFIED THYLAKENTRIN (FSH) AND PURE METAKENTRIN (ICSH)Endocrinology, 1942
- SYNERGISM OF THE FOLLICLE STIMULATING AND LUTEINIZING HORMONES IN PRODUCING OGEN SECRETION1Endocrinology, 1941