Synthesis and antiallergy activity of 4-oxopyrano[3,2-b]indoles
- 1 November 1980
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 23 (11) , 1251-1255
- https://doi.org/10.1021/jm00185a023
Abstract
A series of 4-oxopyrano[3,2-b]indole carboxylic acids, tetrazoles and carboxamidotetrazoles was prepared and tested for antiallergy potential in the rat passive cutaneous anaphylaxis (PCA) assay. Many of the compounds showed activity comparable or superior to that of cromolyn sodium or doxantrazole. Several compounds were orally active.This publication has 7 references indexed in Scilit:
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