Haploinsufficiency for tumour suppressor genes: when you don't need to go all the way
- 7 June 2004
- journal article
- review article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Vol. 1654 (2) , 105-122
- https://doi.org/10.1016/j.bbcan.2004.01.001
Abstract
No abstract availableKeywords
This publication has 99 references indexed in Scilit:
- GermlineTP53 mutations and Li-Fraumeni syndromeHuman Mutation, 2003
- A single mutated BRCA1 allele leads to impaired fidelity of double strand break end-joiningOncogene, 2002
- Evidence that haploinsufficiency ofPtch leads to medulloblastoma in miceGenes, Chromosomes and Cancer, 2000
- The Hallmarks of CancerCell, 2000
- Mutation ofPten/Mmac1in mice causes neoplasia in multiple organ systemsProceedings of the National Academy of Sciences, 1999
- High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in miceCurrent Biology, 1998
- Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formationThe EMBO Journal, 1998
- The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell linesCell, 1991
- The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic miceNature, 1985
- Mutation and Cancer: Statistical Study of RetinoblastomaProceedings of the National Academy of Sciences, 1971