Construction of artificial chromosomes in yeast
- 1 September 1983
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 305 (5931) , 189-193
- https://doi.org/10.1038/305189a0
Abstract
Fifty-five-kilobase [kb] long artificial chromosomes containing cloned genes, replicators, centromeres and telomeres were constructed in yeast. These molecules have many of the properties of natural yeast chromosomes. Centromere function is impaired on short (< 20 kb) artificial chromosomes.This publication has 34 references indexed in Scilit:
- Replication and Resolution of Telomeres in YeastCold Spring Harbor Symposia on Quantitative Biology, 1983
- Centromeric DNA from Saccharomyces cerevisiaeJournal of Molecular Biology, 1982
- Cloning yeast telomeres on linear plasmid vectorsCell, 1982
- Nucleotide sequence comparisons and functional analysis of yeast centromere DNAsCell, 1982
- Two separate regions of the extrachromosomal ribosomal deoxyribonucleic acid of Tetrahymena thermophila enable autonomous replication of plasmids in Saccharomyces cerevisiae.Molecular and Cellular Biology, 1981
- Isolation of a yeast centromere and construction of functional small circular chromosomesNature, 1980
- Isolation and characterisation of a yeast chromosomal replicatorNature, 1979
- High-frequency transformation of yeast by plasmids containing the cloned yeast ARG4 geneProceedings of the National Academy of Sciences, 1979
- A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in TetrahymenaJournal of Molecular Biology, 1978
- Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3).Proceedings of the National Academy of Sciences, 1977