INFLUENCE OF L-THYROXINE ON THE CIRCULATING BASOPHIL LEUCOCYTES IN THE RABBIT

Abstract
The daily intramuscular injection of 25-50 [mu]g thyroxine to rabbits for 6 days results in a steady and linear increase in the number of circulating basophil leucocytes. This increase continues for 2 days after the thyroxine withdrawal. Subsequently, a decrease in basophil -leucocyte count and a rise in endogenously I131-labelled thyroid hormone occur. The inverse relation of release of thyrotropic hormone and circulating basophil leucocytes is discussed.