The Effect of Adenosine, Inosine, and Adenine on the Concentrations of Organic Phosphate and an Electrophoretic Component (B) of Human Red Cells During Storage of Blood in Acid‐Citrate‐Dextrose and Citrate‐Phosphate‐Dextrose*

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Abstract
Bloods, collected in ACD and CPD supplemented with varying amounts of adenosine, inosine, adenine, inosine‐adenosine, inosine‐adenine, and adenosine‐adenine, were stored anaerobically at 4 C for five weeks. At weekly intervals, the Porg, and an electrophoretic boundary (Component B) of the washed red cells were assayed. Generally, these values were higher in the CPD than in the respective ACD bloods during storage. The Porg, and Component B concentrations were maintained at high levels for the ‐ longest periods with CPD bloods supplemented: with 2.0 mmoles adenosine per 100 ml blood and with 1.0 mmole adenosine plus 0.25 or 0.5 mmole adenine. The most rapid decreases in Porg, and Component B were observed in ACD and CPD bloods containing comparatively small amounts of adenine. The relative changes of Porg, and Component B occasionally varied markedly when bloods from different individuals were stored in a given supplemented preservative. A high degree of correlation between Porg, and Component B was noted.