ON THE RELATION OF WHITE BLOOD CELLS AND PLATELETS TO VENOM HEMOLYSIS
Open Access
- 1 October 1956
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 104 (4) , 517-523
- https://doi.org/10.1084/jem.104.4.517
Abstract
Removal of the white cells and platelets from suspensions of red cells usually produces substantial reduction in the hemolytic activity of venoms. Guinea pig red cells constitute a notable exception and may be lysed by a direct action of venom. White blood cells and platelets appear to contribute to hemolysis by serving as sources of phosphatides for the formation of lysophosphatides. No correlation could be found between phospholipase activity and direct hemolytic activity of venoms. A recently described method (8) of paper chromatographic separation of phospholipides has been used successfully in part of the work.Keywords
This publication has 10 references indexed in Scilit:
- Phospholipids. 3. On the chromatographic separation of glycerophospholipidsBiochemical Journal, 1955
- PAPER CHROMATOGRAPHY OF LECITHINSJournal of Biological Chemistry, 1954
- Analysis of lipids by spot tests on filter-paper disk chromatogramsBiochemical Journal, 1953
- Phospholipins. 1. Partition chromatography of egg-yolk phospholipins on celluloseBiochemical Journal, 1953
- PROCEDURES FOR THE MICROESTIMATION OF NITROGENOUS PHOSPHATIDE CONSTITUENTSJournal of Biological Chemistry, 1951
- An electrophoretic examination of cobra venomsBiochemical Journal, 1946
- A comparison of the hemolytic actions of lysolecithin and saponinJournal of Cellular and Comparative Physiology, 1943
- Electrophoresis of Crotoxin*Journal of the American Chemical Society, 1942
- THE LIPID DISTRIBUTION OF HUMAN PLATELETS IN HEALTH AND DISEASE 1Journal of Clinical Investigation, 1939
- Schlangengifte, III. Mitteil.: Reinigung und Krystallisation des Klapperschlangen‐GiftesBerichte der deutschen chemischen Gesellschaft (A and B Series), 1938