Androgens and Erythropoiesis

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Abstract
DURING the past eight years androgen therapy has proved to be efficacious for the anemia of myelofibrosis with myeloid metaplasia.1 2 3 Although our initial report on this subject presented data showing improvement in circulating hemoglobin concentration in the first 9 patients treated2 our subsequent experience has been less fortunate. There is no doubt that some patients with this disorder do not respond favorably to androgen therapy. A few who do not respond favorably may actually worsen as a result of therapy. The purpose of this communication is to present clinical and erythrokinetic data gathered in a group of 21 patients. The . . .