FAILURE OF FOLIC ACID ANTAGONIST TO INTERFERE WITH THE ACTION OF TESTOSTERONE PROPIONATE ON THE COMBS AND TESTES OF YOUNG COCKERELS1

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Abstract
Daily treatment with 100 /[mu]g. of testosterone propionate produced unquestionable growth on the comb and inhibition of the testis of young cockerels placed on a folic acid-deficient diet or a diet containing methyl folic acid. In 2 of the expts. the action of the androgen on the comb appeared to be enhanced. It would appear that while folic acid is necessary for the growth stimulating action of estrogen on the reproductive tract, it is not essential for the growth stimulating action of testosterone on the comb.