Studies ofPanax japonicusFibrinolysis
- 1 February 1989
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 55 (01) , 18-21
- https://doi.org/10.1055/s-2006-961767
Abstract
The effects of a 70% methanol extract (PMe) obtained from the rhizomes of Panax japonicus C.A. Meyer on experimental thrombosis and fibrinolysis were investigated in vivo and in vitro. PMe showed a promotive effect on the activaction of the fibrinolytic system as determined by the euglobulin lysis time (ELT) assay but was inactive to the inhibitory effect against endotoxin-induced disseminated intravascular coagulation (DIC) in rats. PMe and its major components, chikusetsusaponin III, IV, and V, strongly promoted the action of urokinase in fibrin plate. These results suggested that PMe promotes the fibrinolysis and its effective components are chikusetsusaponin III, IV, and V.This publication has 3 references indexed in Scilit:
- Pharmacological study on Panax ginseng C.A. Meyer. IV. Effects of red ginseng on experimental disseminated intravascular coagulation. 3. Effect of ginsenoside-Ro on the blood coagulative and fibrinolytic system.CHEMICAL & PHARMACEUTICAL BULLETIN, 1986
- Pharmacological study on Panax ginseng C. A. Meyer. III. Effects of red ginseng on experimental disseminated intravascular coagulation. (2). Effects of ginsenosides on blood coagulative and fibrinolytic systems.CHEMICAL & PHARMACEUTICAL BULLETIN, 1986
- Pharmacological Study on Panax ginseng C.A. MEYER. I. Effects of Red Ginseng on the Experimental Disseminated Intravascular Coagulation (1)YAKUGAKU ZASSHI, 1983