RESPONSE OF THE SUBMANDIBULAR GLAND OF THE CASTRATED MOUSE TO LOCAL AND SYSTEMIC ADMINISTRATION OF STEROIDS
- 1 July 1963
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 26 (4) , 517-523
- https://doi.org/10.1677/joe.0.0260517
Abstract
SUMMARY: The effects of testosterone propionate (TP) and of 17α-ethyl-19 nor-testosterone (ENT) on the submandibular glands, levator ani muscles and seminal vesicles of castrated mice have been compared. ENT restores submandibular weight and histology about as well as TP but has less effect on the levator ani muscle and much less effect on the seminal vesicles. Both steroids can act directly on the submandibular gland. It is suggested that the effect on the gland may be an indication of the 'anabolic' rather than the 'androgenic' potency of the steroids, and the possible use of this response for the assay of 'anabolic' steroids is discussed.Keywords
This publication has 7 references indexed in Scilit:
- The relation between structure and the concentration of iodide by the submandibular glands of mice and hamstersThe Journal of Physiology, 1963
- Effect of Testosterone Propionate on Tissue Protein Synthesis in the Castrated Male Rat.Experimental Biology and Medicine, 1961
- Myotrophic and Androgenic Activities of Androstanazole. A New Heterocyclic SteroidExperimental Biology and Medicine, 1960
- Comparative Androgenic and Anabolic Effects of Several SteroidsExperimental Biology and Medicine, 1957
- Non-Suitability of Levator Ani Method as an Index of Anabolic Effect of SteroidsExperimental Biology and Medicine, 1957
- THE NECESSITY OF TESTIS AND THYROID HORMONES FOR THE MAINTENANCE OF THE SEROUS TUBULES OF THE SUBMAXILLARY GLAND IN THE MALE RATEndocrinology, 1949
- SEX HORMONE SECRETION BY TUMORS OF THE ADRENAL CORTEX OF MICE1949