Effect of Cola Drinks on Serum Free Fatty Acids

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Abstract
The effect of cola drinks on free fatty acids (FFA) is of considerable interest Diet cola drinks which contain caffeine and artificial sweetener but no sucrose produced significant progressive increase in plasma FFA during the first four hours after ingestion. The regular cola drinks which contain large amounts of sucrose in addition to the caffeine resulted in a decrease in the plasma FFA during the first two to three hours after ingestion, following which there was an increase by the fourth hour. The diminished response of FFA to the cola drinks containing sucrose Is probably due to the suppression of caffeine-in-duced FFA release by the sucrose as a result of its effect on the reesterification of the released FFA. These findings are of interest in view of the relationship of FFA elevation and other lipid fractions, notably, triglycerides and cholesterol.