INCIDENCE AND CAUSES OF HYPERPROTEINEMIA

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Abstract
We had observed 2 cases of relatively common diseases associated with hyperproteinemia (a case of subacute bacterial endocarditis and a case of cirrhosis and primary carcinoma of the liver).1 The simultaneous presence of 2 patients with the supposedly rare condition of hyperproteinemia, lying side by side, in a small (200 bed) semiprivate hospital prompted a study of the incidence and the causes of this condition in our climate and locality. This communication presents the results of a clinical-experimental investigation of this subject in a larger series of patients than has hitherto been reported. LITERATURE Jeghers and Selesnick,2 summarizing the determinations of total plasma protein made by the clinical laboratories of the Boston City Hospital, reported that the incidence of total protein over 8 Gm. per hundred cubic centimeters was 0.2 per cent of 557 determinations in 1934, 1.19 per cent of 526 determinations in 1935 and 2.4 per