Antibiotic Combinations
- 17 January 1957
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 256 (3) , 115-119
- https://doi.org/10.1056/nejm195701172560305
Abstract
THERE has been considerable interest in the past few years in the use of multiple antibacterial agents — engendered, in large measure, by the failure of available antimicrobials adequately to cope with increasing numbers of antibiotic-resistant infections, notably staphylococcal infections in hospitals. This interest has been further stimulated by the possibilities that the combinations will exert a potentiating or synergistic action, broaden the spectrum of antibacterial activity, and avoid or delay the emergence or overgrowth of resistant species or of resistant variants of originally susceptible species of bacteria. Unfortunately, the haphazard and uncontrolled use of multiple antibiotics, as practiced by . . .Keywords
This publication has 5 references indexed in Scilit:
- Antibiotic CombinationsNew England Journal of Medicine, 1956
- Antibiotic CombinationsNew England Journal of Medicine, 1956
- Development of Resistance and Cross-Resistance in vitro to Erythromycin, Carbomycin, Spiramycin, Oleandomycin and Streptogramin.Experimental Biology and Medicine, 1956
- Blood Levels from Orally Administered Penicillins G and VNew England Journal of Medicine, 1955
- Participation of Erythromycin and Carbomycin in Combined Antibiotic Action in vitro.Experimental Biology and Medicine, 1953