EFFICACY OF ISOTONIC SODIUM CHLORIDE AND GLUCOSE SOLUTIONS IN PREVENTING SHOCK FOLLOWING VENOUS OCCLUSION OF A LIMB IN THE DOG

Abstract
The efficacy of isotonic NaCl and of glucose soln. in prevention of the shock syndrome produced by venous occlusion of the hind limb was investigated. NaCl was of more beneficial therapeutic action than glucose, demonstrating that the simple addition of fluid per se is not the sole important factor in preventing this type of shock. The possible beneficial mechanisms of action of NaCl are discussed. Isotonic saline soln., if administered before alteration of capillary permeability has taken place, has a definite place as a therapeutic agent in the treatment of this and possibly other kinds of shock. Its early adm., when other types of blood vol. augmentors are precious or not available, cannot be overemphasized.

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