Effects of Intravenous Administration of Fibrinolysin (Plasmin) in Man
- 1 July 1959
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 20 (1) , 42-55
- https://doi.org/10.1161/01.cir.20.1.42
Abstract
The potentiality of dissolving clots has aroused great interest in fibrinolysin (plasmin) as a therapeutic agent in thromboembolism. In this paper the effects of intravenous administration of purified fibrinolysin in man are reported, with special emphasis upon systemic toxicity and alterations in clotting factors and fibrinolytic activity. This information is necessary for the evaluation of this agent for clinical purposes.Keywords
This publication has 18 references indexed in Scilit:
- The Effect of Heparin on Components of the Human Fibrinolytic SystemBlood, 1958
- THE USE OF PLASMIN IN HUMANSAnnals of the New York Academy of Sciences, 1957
- CLINICAL AND EXPERIMENTAL STUDIES ON FIBRINOLYTIC ENZYMESAnnals of the New York Academy of Sciences, 1957
- Effects in Patients of Intravenous Infusions of Purified Streptokinase Preparations.Experimental Biology and Medicine, 1957
- Stability of the Activator of Bovine PlasminogenExperimental Biology and Medicine, 1956
- Isolation of Partially Purified Human Plasmin (Fibrinolysin)Experimental Biology and Medicine, 1956
- STUDIES WITH CRYSTALLINE TRYPSINJAMA, 1954
- Fibrinolytic and Proteolytic Activity of a Human Plasminogen, Prepared From Fraction III of Human PlasmaJournal of Applied Physiology, 1953
- Influence of anticoagulant administration on the rate of recanalization of experimentally thrombosed veinsBritish Journal of Surgery, 1952
- STUDIES OF STREPTOCOCCAL FIBRINOLYSIS. II. THE INHIBITION OF STREPTOCOCCAL FIBRINOLYSIS BY ANTIFIBRINOLYSIN AND ANTIPROTEASE 1Journal of Clinical Investigation, 1946