Tetramethylpyrazine inhibits activities of glioma cells and glutamate neuro-excitotoxicity: Potential therapeutic application for treatment of gliomas
Open Access
- 1 April 2008
- journal article
- Published by Oxford University Press (OUP) in Neuro-Oncology
- Vol. 10 (2) , 139-152
- https://doi.org/10.1215/15228517-2007-051
Abstract
We tested the herbal extract 2,3,5,6-tetramethylpyrazine (TMP) for possible therapeutic efficacy against a glioma cell line and against gliomas transKeywords
This publication has 45 references indexed in Scilit:
- Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivoNeuro-Oncology, 2005
- Effect of tetramethylpyrazine on potassium channels to lower calcium concentration in cultured aortic smooth muscle cellsClinical and Experimental Pharmacology and Physiology, 2003
- Sources of Reactive Oxygen Species Production in Excitotoxin-Stimulated Cerebellar Granule CellsBiochemical and Biophysical Research Communications, 1999
- Generation of lipid radicals in the hippocampal extracellular space during kainic acid-induced seizures in ratsEpilepsy Research, 1997
- Calcium-dependent free radical generation in cultured retinal neurons injured by kainateNeuroscience Letters, 1995
- Plant‐derived drugs acting on cellular ca 2+ mobilization in vascular smooth muscle: Tetramethylpyrazine and tetrandrineThe International Journal of Cell Cloning, 1994
- Tetramethylpyrazine for treatment of experimentally induced stroke in Mongolian gerbils.Stroke, 1989
- Molecular characterization and expression of the gene encoding human erythroid-potentiating activityNature, 1985
- Control of rat C6 glioma cell proliferation: uncoupling of the inhibitory effects of hydrocortisone hormone in suspension and monolayer cultures.The Journal of cell biology, 1983
- GFA expression in aggregating cultures of rat C6 gliomaCellular and Molecular Life Sciences, 1979