Analysis of Taurine in Blood Plasma of Epileptic Patients Using an Improved Isocratic HPLC Method for Amino Acids
- 1 April 1987
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 10 (5) , 977-995
- https://doi.org/10.1080/01483918708066748
Abstract
An efficient, reversed-phase HPLC method is described in which 21 derivatized amino acids were isocratically separated in less than 90 minutes. An internal standard was used to improve precision and accuracy. The method, which separated taurine from α-, β-, and γ-aminobutyric acids, was used to quantify taurine levels in 83 blood plasma samples. A statistical comparison was made between taurine levels found in the plasma of epileptic and non-epileptic children.Keywords
This publication has 12 references indexed in Scilit:
- Measurement of free amino acids in human biological fluids by high-performance liquid chromatographyJournal of Chromatography A, 1984
- Separation of Orthophthalaldehyde/Ethanethiol Derivatives of Taurine and Closely Eluting Amino Acids by High Performance Liquid ChromatographyJournal of Liquid Chromatography, 1984
- Rapid assay for amino acids in serum or urine by pre-column derivatization and reversed-phase liquid chromatography.Clinical Chemistry, 1982
- Taurine in Nutrition and NeurologyPublished by Springer Nature ,1982
- Quantitative HPLC Analysis of Plasma Amino Acids as Orthophthaldialdehyde/Ethanethiol DerivativesJournal of Liquid Chromatography, 1981
- Separation and Quantitation of O-Phthalaldehyde Derivatives of Taurine and Related Compounds in a High Performance Liquid Chromatography (HPLC) SystemJournal of Liquid Chromatography, 1981
- Amino Acid Analysis and Enzymatic Sequence Determination of Peptides by an Improvedo-Phthaldialdehyde Precolumn Labeling ProcedureJournal of Liquid Chromatography, 1981
- High performance liquid chromatographic determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with o-phthaldialdehydeAnalytical Chemistry, 1979
- High performance liquid chromatographic determination of amino acids in the picomole rangeAnalytical Chemistry, 1979
- High Performance Liquid Chromatographic Separation and Fluorescent Measurement of Taurine, a Key Amino AcidJournal of Liquid Chromatography, 1979