Use of a restriction endonuclease in analyzing the genomes from two different strains of vaccinia virus
- 1 October 1976
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 20 (1) , 319-323
- https://doi.org/10.1128/jvi.20.1.319-323.1976
Abstract
A restriction endonuclease from Haemophilus influenzae (Hind III) specifically cleaved vaccinia DNA into 14 fragments. The molecular weights of these fragments were determined by gel electrophoresis and ranged from 0.5 x 10(6) to 30 x 10(6). Hind III digestion of the DNA from the WR and CV-1 strains of vaccinia revealed a small molecular difference in one of the resulting fragments. The average molecular weight of the entire vaccinia genome was calculated to be 125 x 10(6).This publication has 17 references indexed in Scilit:
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