Antioxidative Properties of Cardoon (Cynara cardunculus L.) Infusion Against Superoxide Radical, Hydroxyl Radical, and Hypochlorous Acid
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- 23 July 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Agricultural and Food Chemistry
- Vol. 50 (17) , 4989-4993
- https://doi.org/10.1021/jf020225o
Abstract
Polyphenols are able to act as antioxidants by virtue of their hydrogen-donating and metal-chelating capacities. Cardoon (Cynara cardunculus L.) is a species containing considerable amounts of polyphenolic compounds, namely flavonoids and phenolic acids. This study examined the antioxidant activity of cardoon lyophilized infusion against superoxide radical, hydroxyl radical, and hypochlorous acid. Superoxide radical was generated either in an enzymatic system or nonenzymatically, and the scavenging ability was assessed by the inhibition of superoxide radical-induced reduction of nitroblue tetrazolium. Hydroxyl radical was generated by the Fe3+-EDTA/ascorbate Fenton system, and scavenging capacity was estimated by evaluating the inhibition of hydroxyl radical-induced deoxyribose degradation into thiobarbituric acid-reactive substances. Inhibition of hypochlorous acid-induced 5-thio-2-nitrobenzoic acid oxidation to 5,5‘-dithiobis(2-nitrobenzoic acid) was used in order to test the hypochlorous acid scavenging activity. Keywords: Cardoon; Cynara cardunculus; antioxidant activity; superoxide radical; hydroxyl radical; hypochlorous acid; polyphenolsKeywords
This publication has 20 references indexed in Scilit:
- The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acidPublished by Elsevier ,2003
- Antioxidant Activity of Centaurium erythraea Infusion Evidenced by Its Superoxide Radical Scavenging and Xanthine Oxidase Inhibitory ActivityJournal of Agricultural and Food Chemistry, 2001
- Identification, Quantitative Determination, and Antioxidative Activities of Chlorogenic Acid Isomers in Prune (Prunus domestica L.)Journal of Agricultural and Food Chemistry, 2000
- Assessing Antioxidant and Prooxidant Activities of Phenolic CompoundsJournal of Agricultural and Food Chemistry, 2000
- Free-radical scavenging action of medicinal herbs from GhanaGeneral Pharmacology: The Vascular System, 1999
- Antioxidant Activity of Selected Medicinal PlantsJournal of Agricultural and Food Chemistry, 1998
- Antioxidative caffeoylquinic acid derivatives in the roots of burdock (Arctium lappa L.).Journal of Agricultural and Food Chemistry, 1995
- Radical Scavenger Activity of Different 3′,4′-Dihydroxyflavonols and 1,5-Dicaffeoylquinic Acid Studied by Inhibition of Chemiluminescence4Planta Medica, 1995
- Characterisation of caffeoylferuloylquinic acids by simultaneous isomerisation and transesterification with tetramethylammonium hydroxideFood Chemistry, 1989
- Characterisation of chlorogenic acids by simultaneous isomerisation and transesterification with tetramethylammonium hydroxideFood Chemistry, 1989