Protective Effect of Adrenal Steroid Administration on Irradiated Mice
- 1 November 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (2) , 397-400
- https://doi.org/10.3181/00379727-81-19888
Abstract
Young male and female DBA mice were exposed to 500 r head radiation or whole-body radiation. A correlation was observed between head and whole-body radiation as judged by the mortality rates. In both instances a 500 r dose gave a 100% mortality rate, but mice receiving whole-body radiation succumbed sooner. Mice receiving 500 r head radiation and treated before or after radiation with cortisone or desoxycorticosterone showed evidence that both of these compounds afford protection from the lethal effect of ionizing radiation.Keywords
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