THE EFFECT OF THE CHRONIC ADMINISTRATION OF ADRENAL MEDULLARY HORMONES TO MAN ON ADRENOCORTICAL FUNCTION AND THE RENAL EXCRETION OF ELECTROLYTES

Open Access
Publisher Website
Google Scholar
Abstract
The admn. of epinephrine to normal men in a dosage of from 6 to 9 mg. per day for periods of 3-6 days proved to be no more than a very weak chronic stimulus to adrenocortical activity as estimated by the level of circulating eosinophils and the urinary 17-ketosteroids and formaldehydo-genic steroids. Epinephrine in this dosage resulted in increased urinary excretion of Na, chloride, Ca, and uric acid, and diminished urinary excretion of K.