LYMPHOSARCOMA WITH LEUKEMIA IN A HORSE

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  • 1 January 1982
    • journal article
    • research article
    • Vol. 43  (5) , 807-812
Abstract
A 17-yr-old Arabian gelding was presented because of CNS depression and weight loss. Physical examination revealed generalized lymphadenopathy, pitting edema and ascites. The diagnosis of lymphosarcoma with leukemic manifestations was based on cytologic and histopathologic examination of lymph node biopsy samples and a peripheral leukocyte count of 98,300/.mu.l, 94% of which were mature lymphocytes. These circulating lymphocytes lacked B-lymphocyte markers and did not respond to mitogenic stimulation, indicating functional incompetence. Though ultrastructural findings were equivocal, most morphologic changes indicated these cells were of T lymphocyte lineage.