Genetic variation at a pig serum protein locus, Po‐2 and its assignment to the Phi, Hal, S, H, Pgd linkage group
- 1 January 1983
- journal article
- research article
- Published by Wiley in Animal Blood Groups and Biochemical Genetics
- Vol. 14 (1) , 27-36
- https://doi.org/10.1111/j.1365-2052.1983.tb01057.x
Abstract
Summary: Two‐dimensional agarose gel (pH 5.4)‐polyacrylamide gel (pH 9.0) electropho‐resis of pig serum samples revealed a new serum protein (postalbumin‐2, PO‐2) polymorphism. Family data supported the hypothesis that the three PO‐2 phenotypes observed were controlled by two codominant, autosomal alleles (Po‐2F and Po‐2S) at a single locus. The frequency of Po‐2F in Swedish Landrace and in Swedish Yorkshire breeds was estimated at 0.74 and 0.65, respectively. Evidence was presented for close genetic linkage between Po‐2 and the red cell phospho‐hexose isomerase locus (Phi). A recombination frequency of 3.2 % was obtained from double backcross material. Data obtained in a Danish Landrace material showing linkage between the Po‐2 locus and the H blood group locus, the Pgd locus and Hal (locus for halothane sensitivity) are also given. A total of seven re‐combinants were observed. They show that Po‐2 is a new locus in a previously established linkage group. The likely sequence of the loci is: Phi, Hal, S, H, Po‐2, Pgd.Keywords
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