Late Acting T Cell Depression of High Avidity IgG Antibody Secretion in the Secondary Response
Open Access
- 1 November 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 119 (5) , 1806-1812
- https://doi.org/10.4049/jimmunol.119.5.1806
Abstract
Activated T lymphocytes (ATC) suppressed the expression of high avidity plaque-forming cells (PFC) in the secondary immune response when given in vivo 1 day before assay or when mixed in vitro with hyperimmune cells for 90 min before assay. This late acting suppression is a cell dose-dependent, carrier-specific, T cell-mediated phenomenon. The target of this activity is probably the antibody-secreting cell.This publication has 10 references indexed in Scilit:
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