Determination of Clobazam, n-desmethylclobazam and their hydroxy metabolites in plasma and urine by high-performance liquid chromatography

This publication has 26 references indexed in Scilit:

• High performance liquid chromatographic analysis of basic drugs on silica columns using non-aqueous ionic eluents
  Journal of Chromatography A, 1982
• Liquid Chromatography Determination of Clobazam and Its Major Metabolite N-Desmethylclobazam in Human Plasma
  Therapeutic Drug Monitoring, 1982
• Electron-capture GLC determination of clobazam and desmethylclobazam in plasma
  Journal of Pharmaceutical Sciences, 1980
• Four benzodiazepine radioimmunoassays are described, the most sensitive of which can detect sub-therapeutic levels of bromazepam, chlordiazepoxide, clobazam, demoxepam, desalkylflurazepam, desmethyldiazepam, diazepam, flunitrazepam, lorazepam, medazepam, nitrazepam, oxazepam, prazepam, temazepam and triazolam. The standard curve for diazepam has a concentration range of 0–2·5 ng ml The assay is particularly applicable to blood samples of forensic interest that may be haemolysed or decomposing. A 75 μI sample is required. The antiserum and [3 H]flunitrazepam used are commercially available
  Journal of Pharmacy and Pharmacology, 1980
• Clobazam
  Drugs, 1980
• Plasma Levels of Clobazam after 10‐, 20‐, and 40‐mg Tablet Doses in Healthy Subjects
  The Journal of Clinical Pharmacology, 1980
• Antiepileptic Properties of Clobazam, a 1–5 Benzodiazepine, in Man
  Epilepsia, 1979
• Fluorometric Determination of Clobazam, a 1,5-Benzodiazepine, in Human Plasma
  Journal of Pharmaceutical Sciences, 1979
• Plasma Levels of Clobazam After Three Oral Dosage Forms in Healthy Subjects
  The Journal of Clinical Pharmacology, 1978
• Anticonvulsant Action of a 1,5‐Benzodiazepine, Clobazam, in Reflex Epilepsy
  Epilepsia, 1978