Further Evaluation of Animal Systemic Insecticides, 1964

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Abstract
Results of screening tests of 5 candidate materials are presented. In the screening test, larvae of the secondary screw-worm, Cochliomyia macellaria (F.), and of the black blow fly, Phormia regina (Meigen), have replaced larvae of the screw-worm, Cochliomyia hominivorax (Coquerel). Guinea pigs infested with all 3 species were treated with 5 systemic insecticides. Results indicated that larvae of the secondary screw-worm and black blow fly are not so susceptible to systemic insecticides as screw-worm larvae, but can be used in the screening program. Results of tests with 17 insecticides administered to Government-owned cattle for control of cattle grubs, Hypoderma spp., are presented. Treatments highly effective against cattle grubs were: Bayer 37341 (O,O-diethyl O-[4- (methylthio) -3,5-xylyl] phosphorothioate), as a pour-on of 250 ml/head of 2% in oil or in feed at 1 mg/kg/day for 10 days; Bayer 37342 (O,O-dimethyl O-[4-(methylthio) -3,5-xylyl] phosphorothioate), in feed at 2.5 mg/kg/ day for 10 days; coumaphos (11.6% emulsifiable concentrate) as a pour-on of 250 ml/head of 2% in oil; Famophos (O-p- (dimethylsulfamoyl) phenyl O,O-dimethyl phosphorothioate), as a pour-on of 100 ml/head of 16.7% or 55 ml/head of 12.5% and in feed at 5 mg/kg/day for 10 days; Imidan® (O,O-dimethyl S-phthalimidomethyl phosphorodithioate), as a pour-on of 65 ml/head of 2% in oil, an intramuscular injection of 5 mg/kg, or a 0.25% spray; Stauffer R-3828 (S- (p-chlorophenyl) phenylmethyl 0,0-diethyl phosphorodithioate) at 25 mg/kg by capsule; and trichlorfon as a 0.25% spray.

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