METABOLISM OF THE STEROID HORMONES. ADRENAL CORTICAL-LIKE MATERIAL IN HUMAN URINE1
- 1 August 1944
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 35 (2) , 121-125
- https://doi.org/10.1210/endo-35-2-121
Abstract
By means of a cold protection test using adrenalec-tomized rats, cortin-like material was demonstrated in the urine of 9 normal men and 8 normal women. Cortin-like material could be demonstrated only once in 15 assays in urines from 7 patients with Addison''s disease. This material presumably arises in the adrenal cortex, and variations in urinary content reflect the physiological activity of the gland. The adm. of adrenal cortical extracts to patients with Addison''s disease resulted in the excretion of cortin-like material. Orally administered desoxycorticosterone had no such effect.This publication has 5 references indexed in Scilit:
- TREATMENT OF ADDISONʼS DISEASE WITH PELLETS OF DESOXYCORTICOSTERONE ACETATEThe Lancet Healthy Longevity, 1944
- THE PRESENCE IN NORMAL URINE OF CORTIN-LIKE MATERIAL WHICH IS ACTIVE IN A MUSCLE WORK TESTAmerican Journal of Physiology-Legacy Content, 1943
- THE EFFECT OF URINARY CORTIN-LIKE MATERIAL ON CARBOHYDRATE METABOLISMScience, 1943
- The Presence of a Cortin-Like Substance (Cold Protecting Material) in the Urine of Normal MenScience, 1942
- HORMONE AND ELECTROLYTE STUDIES OF PATIENTS WITH HYPERADRENOCORTICAL SYNDROME (CUSHING'S SYNDROME)1Endocrinology, 1938