Novel designed enediynes: Molecular design, chemical synthesis, mode of cycloaromatization and guanine-specific DNA cleavage
- 31 January 1996
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 4 (1) , 105-113
- https://doi.org/10.1016/0968-0896(95)00170-0
Abstract
No abstract availableKeywords
This publication has 75 references indexed in Scilit:
- Switching from the Myers Reaction to a New Thermal Cyclization Mode in Enyne-AllenesTetrahedron Letters, 1995
- Synthesis of a Nine-Membered Ring via the Intramolecular Ni(II)/Cr(II)-Mediated Coupling Reaction. Unusual Effect of Concentration on the Course of the ReactionSynthetic Communications, 1994
- Novel synthesis of a chiral cyclic dienediyne system related to the neocarzinostatin chromophoreJournal of the Chemical Society, Chemical Communications, 1992
- Synthesis of the 4,5-epoxybicyclo[7.3.0]dodecadiyne neocarzinostatin core structure. Surprising compatibility of the 4,5-epoxide with a η2-hexacarbonyldicobalt mediated aldol reactionJournal of the Chemical Society, Chemical Communications, 1991
- The novel selenium mediated aromatization of a 1,6-diyn-3-ene system related to neocarzinostatin chromophoreJournal of the Chemical Society, Chemical Communications, 1991
- Synthesis of the neocarzinostatin chromophore A core diynene structure using an η2-hexacarbonyidicobalt mediated Aldol reactionJournal of the Chemical Society, Chemical Communications, 1991
- The 10-membered ring analogs of neocarzinostatin chromophore: design, synthesis and mode of decompositionJournal of the American Chemical Society, 1989
- Cyclic conjugated enediynes related to calicheamicins and esperamicins: calculations, synthesis, and propertiesJournal of the American Chemical Society, 1988
- Mechanism and base specificity of DNA breakage in intact cells by neocarzinostatinBiochemistry, 1987
- Neocarzinostatin chromophore: Presence of a highly strained ether ring and its reaction with mercaptan and sodium borohydrideBiochemical and Biophysical Research Communications, 1983