The combination of pivmecillinam and pivampicillin in the treatment of enteric fever
- 1 November 1984
- journal article
- research article
- Published by Springer Nature in Infection
- Vol. 12 (6) , 381-383
- https://doi.org/10.1007/bf01645219
Abstract
Summary Thirty-nine patients with acute enteric fever received the fixed-dose oral combination of pivmecillinam/pivampicillin. Thirty-seven (95%) subjects responded satisfactorily. No relapses or persistent faecal excretion of salmonellae were seen in the 29 patients followed up for 2 to 19 weeks. The treatment was well tolerated, no side-effects being recorded.In vitro studies revealed a synergistic interaction between mecillinam and ampicillin against isolates ofSalmonella paratyphi A.Keywords
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