SOME ASPECTS OF THE ROLE OF PITUITARY HORMONES IN CALCIUM METABOLISM

Abstract
Intact or hypophysectomized young male rats were pre-treated with ACTH 0.5-1.0 mg. twice daily for 19-22 days, then given Ca45 intraven. and sacrificed at intervals up to 24 hrs. Hypophysectomy was associated with increased serum Ca45 decreased uptake of Ca45 by tibial epiphysis and decreased Ca45 ''in the feces. ACTH did not affect the Ca metabolism. Pitressin (up to 10 U/day) tended to decrease the urinary and fecal Ca45 excretion.