Toxicity of Several Organophosphates Administered in the Diet of Broilers to House Fly Larvae in the Feces1

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Abstract
Ronnel, butonate, Ruelene® (O-4-tert-butyl-2-chlorophenyl O-methyl methylphosphoramidate), Bayer 29493 (O, O-dimethyl O-[4-(methylthio)-,m-tolyl] phosphorothioate), Bayer 22408 (naphthalimido-O, O-diethyl phosphorothionte), Bayer 34098 (O,(4-methylthio-m-tolyl) dimethyl phosphinothioate) and Bayer 37342 (O, O-dimethyl O-(3,5-dimethyl-4-methylthiophenyl) phosphorothioate) were mixed in poultry-growing mash at 50, 100, 200, 400, and 800 p.p.m. and fed to 5- to 7-week-old broilers for 7 days. Bayer 22408, Bayer 29493, Bayer 34098, and Bayer 37342 at all concentration levels in the feed resulted in 100% control of house fly (Musca domestica L.) in the feces. Ronnel was effective at the 200, 400, and 800 p.p.m. levels, but was ineffective at the lower concentrations against house fly larvae; butonate and Ruelene were ineffective. Polymer and nonpolymer formulations of Bayer 22408 in the feed were equally effective against 1- and 3-day-old house fly larvae in poultry droppings. Negative gains in weight were observed of birds receiving Bayer 29493 and Bayer 37342 at 200 p.p.m. or higher in the feed. Fifty per cent of the broilers died that were on feed containing 400 or 800 p.p.m. Bayer 37342.