Synthetic studies on 1-carbacephem antibiotics: New synthetic approach to 3H-carbacephems.
- 31 December 1987
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 36 (9) , 3642-3645
- https://doi.org/10.1248/cpb.36.3642
Abstract
A new synthetic route to 3-H (3-unsubstituted) carbacephems was developed starting from readily available dialkyl aminomalonate and using intra-molecular aldol condensation for the construction of the 4, 6-fused ring system.Keywords
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