Inhibitors of adenosine 3',5'-cyclic monophosphate phosphodiesterase in Daphne genkwa SIEB. et ZUCC.

Abstract
Luteolin, luteolin-7-methyl ether and kaempferol 3-O-.beta.-D-(6"-p-coumaroyl)glucopyranoside-(tiliroside) were identified as cyclic AMP phosphodiesterase inhibitors contained in the flowers and buds of Daphne genkwa SIEB.et ZUCC. The assignments of the proton and carbon-13 NMR signals of tiliroside were confirmed by two-dimensional 1H-13C chemical shift correlation spectroscopy.